A Case of Solitary Subependymal Giant Cell Astrocytoma
نویسندگان
چکیده
منابع مشابه
[Subependymal giant cell astrocytoma (tuberous sclerosis)].
Two cases of tuberous sclerosis with subependymal giant cell astrocytoma are presented. This rare autosomal dominant disorder was also detected in family members of the patients who had never had any symptoms of cerebral involvement. Both patients underwent surgery because of signs of increased intracranial pressure.
متن کامل[Solitary subependymal giant cell astrocytoma: a forme fruste of tuberous sclerosis complex?].
Subependymal giant cell astrocytoma (SEGA) is usually associated with tuberous sclerosis (TS) and believed to originate from subependymal nodules. We report a rare case of SEGA in a patient lacking symptoms of TS. Radiological findings, including CT and MRI, were characteristic of SEGA, but the preoperative diagnosis was difficult due to the fact that no other features of TS were present. TS ha...
متن کاملErk activation as a possible mechanism of transformation of subependymal nodule into subependymal giant cell astrocytoma.
INTRODUCTION Subependymal nodule (SEN) and subependymal giant cell astrocytoma (SEGA) are brain lesions frequently found in tuberous sclerosis (TS). As about 10-15% of SENs enlarge and transform into SEGAs, we examined here the possible mechanism of the phenomenon. MATERIAL AND METHODS Using Western blot we studied 1 SEN and 3 SEGA samples; SEN and 1 SEGA came from the same TS patient. We eva...
متن کاملThe Clinical Characteristics of Subependymal Giant Cell Astrocytoma: Five Cases
In this study, we reviewed the clinical characteristics of five cases of subependymal giant cell astrocytoma (SEGA) at our hospital between May 1997 and July 2012. The median age was 18 years old (range, 8 to 26). The clinical symptoms were presented as seizure in two patients and headache in three patients. All the tumors were located near the foramen of Monro. The median size of the tumors wa...
متن کاملEverolimus for subependymal giant cell astrocytoma: 5‐year final analysis
OBJECTIVE To analyze the cumulative efficacy and safety of everolimus in treating subependymal giant cell astrocytomas (SEGA) associated with tuberous sclerosis complex (TSC) from an open-label phase II study (NCT00411619). Updated data became available from the conclusion of the extension phase and are presented in this ≥5-year analysis. METHODS Patients aged ≥ 3 years with a definite diagno...
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ژورنال
عنوان ژورنال: The Journal of Molecular Diagnostics
سال: 2005
ISSN: 1525-1578
DOI: 10.1016/s1525-1578(10)60586-7